⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1169137 | 0.87 | ALDH1A1 (0.50) | — | |
| SCHEMBL14265339 | 0.81 | KDM4E (0.39) | — | |
| SCHEMBL8423451 | 0.78 | HDAC3 (0.52) | — | |
| SCHEMBL606948 | 0.77 | — | — | |
| SCHEMBL2113139 | 0.77 | — | — | |
| SCHEMBL13209882 | 0.77 | MGAM (0.39) | — | |
| SCHEMBL29039515 | 0.77 | ALDH1A1 (0.43) | — | |
| SCHEMBL28174433 | 0.77 | — | — | |
| SCHEMBL11244426 | 0.77 | — | — | |
| SCHEMBL18900550 | 0.76 | ALDH1A1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105198789-B | Substitute 3- indoles Bcl-2 protein inhibitors and preparation method and application | 山东大学 | 2018-06-05 | — | — | CN | claimed |
| US-4960873-A | 3-pyridylisothiazoleazo compounds useful as disperse dyes | BASF AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | claimed |
| US-20240368072-A1 | METHOD FOR PREPARATION OF N-ACETYL CYSTEINE AMIDE OR DI- N-ACETYL CYSTEINE AMIDE AND DERIVATIVES | NACUITY PHARMACEUTICALS, INC. | 2024-11-07 | — | — | US | disclosed |
| US-20240342118-A1 | METHOD FOR PREPARATION OF N-ACETYL CYSTEINE AMIDE OR DI- N-ACETYL CYSTEINE AMIDE AND DERIVATIVES | NACUITY PHARMACEUTICALS, INC. | 2024-10-17 | — | — | US | disclosed |
| US-20230346951-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | YALE UNIVERSITY | 2023-11-02 | — | — | US | disclosed |
| CN-116462818-A | Color-change-resistant antibacterial thermoplastic polyurethane elastomer, preparation method and application thereof | 万华化学集团股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| EP-3534890-A1 | METHODS OF MAKING DEUTERIUM-ENRICHED N-ACETYLCYSTEINE AMIDE (D-NACA) AND (2R,2R')-3,3' -DISULFANEDIYL BIS(2-ACETAMIDOPROPANAMIDE) (DINACA) AND USING D-NACA AND DINACA TO TREAT DISEASES INVOLVING OXIDATIVE STRESS | NaCuity Pharmaceuticals, Inc. (US) | 2019-09-11 | — | — | EP | disclosed |
| CN-105198789-B | Substitute 3- indoles Bcl-2 protein inhibitors and preparation method and application | 山东大学 | 2018-06-05 | — | — | CN | disclosed |
| US-20170253614-A1 | HEPATITIS C VIRUS INHIBITORS AND USES THEREOF IN PREPARATION OF DRUGS | CHANGZHOU YINSHENG PHARMACEUTICAL CO., LTD. (CN) | 2017-09-07 | — | — | US | disclosed |
| US-9561216-B2 | Alkylamine derivative | EA PHARMA CO., LTD. (JP) | 2017-02-07 | — | — | US | disclosed |
| US-20160268515-A1 | TRIAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE WITH THE USE OF TRIAZOLE DERIVATIVE | SEMICONDUCTOR ENERGY LAB (JP) | 2016-09-15 | — | — | US | disclosed |
| US-20010001101-A1 | Phenanthroline derivatives | ZENECA LIMITED | 2001-05-10 | — | — | US | disclosed |
| EP-1027351-A1 | PHENANTHROLINE DERIVATIVES | FIBROGEN, INC. (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5916898-A | ANTIFIBROPROLIFERTIVE, ENZYME INHIBITORS OF PYROLYL 4-HYDROXYLASE, ANTIARTHRITIC AGENTS | ZENECA LIMITED (GB) | 1999-06-29 | — | — | US | disclosed |
| WO-1999021860-A1 | PHENANTHROLINE DERIVATIVES | FIBROGEN, INC. (US) | 1999-05-06 | — | — | WO | disclosed |
| US-5843628-A | Color image formation method | FUJI PHOTO FILM CO., LTD. (JP) | 1998-12-01 | — | — | US | disclosed |
| CN-1097417-A | New heterogeneous ring compound | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-01-18 | — | — | CN | disclosed |
| US-4789675-A | HYPOTENSIVE, ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-12-06 | — | — | US | disclosed |
| US-4544660-A | DOPAMINE ANTAGONIST | BEECHAM GROUP P.L.C. (GB) | 1985-10-01 | — | — | US | disclosed |
| US-4065254-A | DIAZO DYES, LEATHER, COTTON, WOOL | CIBA-GEIGY CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |