Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.69 |
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981473 | 0.79 | CES2 (0.56) | HDAC6HDAC1CES2CES1HDAC2 | |
| SCHEMBL26227516 | 0.79 | KDM4E (0.59) | HDAC6HDAC1CES2CES1CA1 | |
| SCHEMBL11797156 | 0.79 | HDAC6 (0.58) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL25567670 | 0.79 | HDAC6 (0.60) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL13485807 | 0.78 | HDAC6 (0.63) | HDAC6HDAC1CES2CES1HDAC3 | |
| SCHEMBL30929656 | 0.77 | HDAC6 (0.69) | HDAC6HDAC1CES2CES1HDAC3 | |
| SCHEMBL28623180 | 0.77 | HDAC6 (0.69) | HDAC6HDAC1CES2CES1HDAC3 | |
| SCHEMBL25569531 | 0.77 | HDAC6 (0.58) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL31048985 | 0.76 | HDAC6 (0.56) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL22503185 | 0.74 | CES2 (0.45) | HDAC6HDAC1CES2CES1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150950-A2 | ANTHRANILIC ACID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 2001-11-07 | — | — | EP | claimed |
| WO-2000041505-A2 | ANTHRANILIC ACID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 2000-07-20 | — | — | WO | claimed |