Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 17/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31174965 | 0.81 | TTR (0.52) | ACLYCA12CA1CA9HSD17B10 | |
| SCHEMBL31049112 | 0.81 | TTR (0.52) | ACLYCA12CA1CA9HSD17B10 | |
| SCHEMBL31049040 | 0.81 | CES2 (0.35) | HDAC6HDAC1ALOX15 | |
| SCHEMBL17041582 | 0.79 | CA5A (0.39) | HDAC6HDAC1ALOX15 | |
| SCHEMBL31049141 | 0.79 | KDM4E (0.47) | ACLYCA12CA1CA9 | |
| SCHEMBL31048991 | 0.76 | HDAC1 (0.36) | HDAC6HDAC1HDAC3HDAC2 | |
| SCHEMBL7799136 | 0.76 | HDAC6 (0.69) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL13485779 | 0.76 | HDAC6 (0.58) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL27026775 | 0.71 | KDM4E (0.55) | HDAC6HDAC1CA1CA9 | |
| SCHEMBL11797156 | 0.70 | HDAC6 (0.58) | HDAC6HDAC1HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024167922-A2 | HETEROCYCLIC COMPOUNDS AS NRAS INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-08-15 | — | — | WO | disclosed |