Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453933 | 0.78 | TSHR (0.40) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL29000737 | 0.78 | TSHR (0.40) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL28940146 | 0.76 | FDPS (0.34) | TSHRTHRBALDH1A1 | |
| SCHEMBL8908221 | 0.75 | TSHR (0.30) | TSHRALDH1A1 | |
| SCHEMBL2123927 | 0.74 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL367147 | 0.74 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL18406142 | 0.74 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL5843537 | 0.74 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL20857010 | 0.74 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL81296 | 0.74 | TSHR (0.47) | TSHRTHRBALDH1A1DNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980870-B1 | Process for preparing silanes substituted at position alpha of the silicon atom by a tertiary hydrocarbon group | WACKER CHEMIE GMBH (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6156918-A | Process for the preparation of silanes, with a tertiary hydrocarbon group in the a-position relative to the silicon atom | WACKER-CHEMIE GMBH (DE) | 2000-12-05 | — | — | US | disclosed |
| EP-0980870-A1 | Process for preparing silanes substituted at position alpha of the silicon atom by a tertiary hydrocarbon group | Wacker-Chemie GmbH (DE) | 2000-02-23 | — | — | EP | disclosed |