Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799202 | 0.78 | KDM4E (0.38) | SMN1; SMN2MEN1KMT2AGLAKDM4E | |
| SCHEMBL7806630 | 0.76 | KEAP1 (0.42) | SMN1; SMN2GLAKDM4EKEAP1ALDH1A1 | |
| SCHEMBL7806632 | 0.76 | KEAP1 (0.42) | SMN1; SMN2GLAKDM4EKEAP1ALDH1A1 | |
| SCHEMBL4781372 | 0.76 | DRD3 (0.43) | GLAMAPK1ALDH1A1SIGMAR1 | |
| SCHEMBL1830029 | 0.76 | DRD3 (0.43) | GLAMAPK1ALDH1A1SIGMAR1 | |
| SCHEMBL4781369 | 0.76 | DRD3 (0.43) | GLAMAPK1ALDH1A1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8193410 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AGLAKDM4E | |
| Hydrochloric Acid SCHEMBL8193411 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AGLAKDM4E | |
| Hydrochloric Acid SCHEMBL7804679 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AGLAKDM4E | |
| Hydrochloric Acid SCHEMBL7804681 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AGLAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710662-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | SYNGENTA LTD (GB) | 2001-04-04 | — | — | EP | disclosed |
| EP-1018513-A2 | Quinolinecarboxylic acid derivatives | ZENECA LIMITED (GB) | 2000-07-12 | — | — | EP | disclosed |
| EP-0710662-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1996-05-08 | — | — | EP | disclosed |