Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799252 | 0.78 | SMN1; SMN2 (0.40) | KDM4EALDH1A1MAPK1SMN1; SMN2MEN1 | |
| SCHEMBL6941674 | 0.73 | ALDH1A1 (0.47) | KDM4EALDH1A1MAPK1HIF1AHPGD | |
| SCHEMBL8108818 | 0.73 | ALDH1A1 (0.47) | KDM4EALDH1A1MAPK1HIF1AHPGD | |
| Hydrochloric Acid SCHEMBL7805841 | 0.71 | SIGMAR1 (0.35) | — | |
| SCHEMBL7799285 | 0.70 | GBA1 (0.35) | OPRM1OPRD1 | |
| SCHEMBL7806630 | 0.69 | KEAP1 (0.42) | KDM4EALDH1A1HPGDDUSP3SMN1; SMN2 | |
| SCHEMBL7806632 | 0.69 | KEAP1 (0.42) | KDM4EALDH1A1HPGDDUSP3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8193410 | 0.68 | SMN1; SMN2 (0.41) | KDM4EALDH1A1HPGDDUSP3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7804679 | 0.68 | SMN1; SMN2 (0.41) | KDM4EALDH1A1HPGDDUSP3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8193411 | 0.68 | SMN1; SMN2 (0.41) | KDM4EALDH1A1HPGDDUSP3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710662-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | SYNGENTA LTD (GB) | 2001-04-04 | — | — | EP | disclosed |
| EP-1018513-A2 | Quinolinecarboxylic acid derivatives | ZENECA LIMITED (GB) | 2000-07-12 | — | — | EP | disclosed |
| EP-0710662-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1996-05-08 | — | — | EP | disclosed |