Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8183912 | 1.00 | GBA1 (0.35) | GBA1DRD2DRD4DRD3SMYD3 | |
| Hydrochloric Acid SCHEMBL7806303 | 0.98 | GBA1 (0.34) | GBA1DRD2DRD4DRD3SMYD3 | |
| Hydrochloric Acid SCHEMBL7806305 | 0.98 | GBA1 (0.34) | GBA1DRD2DRD4DRD3SMYD3 | |
| SCHEMBL96271 | 0.83 | GBA1 (0.41) | GBA1SMYD3 | |
| SCHEMBL26157412 | 0.82 | GBA1 (0.36) | GBA1DRD2DRD4DRD3SMYD3 | |
| SCHEMBL7805795 | 0.81 | LMNA (0.38) | DRD2DRD4DRD3 | |
| SCHEMBL7805796 | 0.81 | LMNA (0.38) | DRD2DRD4DRD3 | |
| SCHEMBL23588763 | 0.80 | DRD2 (0.37) | GBA1DRD2DRD4DRD3 | |
| SCHEMBL14967796 | 0.80 | GBA1 (0.35) | GBA1DRD2DRD4DRD3SMYD3 | |
| SCHEMBL14967799 | 0.80 | LMNA (0.50) | GBA1DRD2DRD4DRD3SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710662-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | SYNGENTA LTD (GB) | 2001-04-04 | — | — | EP | disclosed |
| EP-1018513-A2 | Quinolinecarboxylic acid derivatives | ZENECA LIMITED (GB) | 2000-07-12 | — | — | EP | disclosed |
| EP-0710662-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1996-05-08 | — | — | EP | disclosed |