SCHEMBL7799451

SCHEMBL7799451

Clc1ccc(C2=CCC2)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.56
HTR2C P28335 1/20 0.54
LMNA P02545 1/20 0.44
CYP2A6 P11509 1/20 0.44
CYP1A2 P05177 1/20 0.43
SLC18A3 Q16572 1/20 0.40
LSS P48449 1/20 0.39
AHR P35869 1/20 0.39
POLB P06746 1/20 0.38
PTPN11 Q06124 1/20 0.38
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37
TSHR P16473 1/20 0.37
GCGR P47871 1/20 0.37
ALOX5 P09917 1/20 0.36
HTR1A P08908 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL511919 0.82 SIGMAR1 (0.50) SIGMAR1HTR2CLMNACYP2A6CYP1A2
SCHEMBL5406706 0.80 SIGMAR1 (0.48) SIGMAR1HTR2CSLC18A3LSSALDH1A1
SCHEMBL28560407 0.80 SIGMAR1 (0.52) SIGMAR1HTR2CLMNACYP2A6CYP1A2
SCHEMBL14704901 0.75 SIGMAR1 (0.69) SIGMAR1HTR2C
SCHEMBL5151774 0.74 SIGMAR1 (0.43) SIGMAR1HTR2CCYP1A2SLC18A3
SCHEMBL9377713 0.74 HTR2C (0.62) HTR2CTSHRALOX5
SCHEMBL8181096 0.74 SIGMAR1 (0.38) SIGMAR1HTR2CLMNACYP2A6CYP1A2
SCHEMBL13221420 0.72 MAPK14 (0.40) SIGMAR1LMNAPOLBKDM4EALDH1A1
SCHEMBL9347469 0.72 CXCR3 (0.34) SIGMAR1HTR2C
SCHEMBL9124531 0.72 IDO1 (0.37) SIGMAR1HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250026869-A1 Benzocyclobutene Resins Containing Olefinic Bonds and Preparing Methods Thereof WUHAN DESYTEK ENVIRONMENTAL PROTECTION & NEW MATERIALS CO., LTD. (CN) 2025-01-23 US claimed
CN-119039588-A Siloxane benzocyclobutene prepolymer, solvent-free high-temperature-resistant low-dielectric ink for inkjet 3D printing, and preparation method and application thereof 大连理工大学 2024-11-29 CN claimed
WO-2024113697-A1 BENZOCYCLOBUTENE RESIN CONTAINING OLEFINIC BOND, AND PREPARATION METHOD THEREFOR 武汉迪赛环保新材料股份有限公司 2024-06-06 WO claimed
CN-117106173-A Thermosetting low dielectric polyphenyl ether resin polymer and preparation method thereof 四川轻化工大学 2023-11-24 CN claimed
CN-117069878-A Hydrogenated resin, preparation method thereof, dielectric material, plate and electric device 华为技术有限公司 2023-11-17 CN claimed
CN-117069877-A Modified resin and preparation method thereof, dielectric material, plate and electric device 华为技术有限公司 2023-11-17 CN claimed
WO-2023216979-A1 HYDROGENATED RESIN AND PREPARATION METHOD THEREFOR, DIELECTRIC MATERIAL, SHEET MATERIAL, AND ELECTRICAL DEVICE 华为技术有限公司 2023-11-16 WO claimed
WO-2023216980-A1 MODIFIED RESIN AND PREPARATION METHOD THEREFOR, DIELECTRIC MATERIAL, SHEET MATERIAL, AND ELECTRICAL DEVICE 华为技术有限公司 2023-11-16 WO claimed
CN-115991808-B Benzocyclobutene resin containing olefinic bond and preparation method thereof 武汉迪赛环保新材料股份有限公司 2023-11-03 CN claimed
CN-115991808-A Benzocyclobutene resin containing olefinic bond and preparation method thereof 武汉迪赛新材料有限公司 2023-04-21 CN claimed
CN-108178720-B Synthetic method of 4-cyclobutyl biphenyl fluorine-containing compound 山东盛华新材料科技股份有限公司 2021-04-13 CN claimed
US-4960956-A Modified bisphenols having at least one arylcyclobutenealkyl moiety and cured products therefrom SHELL OIL COMPANY (US) 1990-10-02 US claimed
CN-122036805-A Compound containing phosphaphenanthrene bonded benzocyclobutene, and preparation method and application thereof 武汉迪赛环保新材料股份有限公司 2026-05-15 CN disclosed
US-20250026869-A1 Benzocyclobutene Resins Containing Olefinic Bonds and Preparing Methods Thereof WUHAN DESYTEK ENVIRONMENTAL PROTECTION & NEW MATERIALS CO., LTD. (CN) 2025-01-23 US disclosed
CN-119119330-A Halogen-free flame-retardant modified hydrocarbon resin, preparation method thereof, resin composition for copper-clad plate and application thereof 四川东材科技集团成都新材料有限公司 2024-12-13 CN disclosed
CN-119039588-A Siloxane benzocyclobutene prepolymer, solvent-free high-temperature-resistant low-dielectric ink for inkjet 3D printing, and preparation method and application thereof 大连理工大学 2024-11-29 CN disclosed
US-4978721-A HEAT CURABLE POLYMER HAVING AT LEAST ONE PENDANT CARBOXYLIC ACID ESTERIFIED WITH AN ALKYL ARYLCYCLOBUTENE GROUP SHELL OIL COMPANY (US) 1990-12-18 US disclosed
EP-0397276-A2 Functionalized elastomeric polymers SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-11-14 EP disclosed
US-4898999-A Process for halogenating cyclobutenoarenes SHELL OIL COMPANY (US) 1990-02-06 US disclosed
EP-0346959-A1 Process for halogenating cyclobutenoarenes SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-12-20 EP disclosed