Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA7 | P43166 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158525 | 0.80 | CA12 (0.46) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL190088 | 0.79 | KMT2A (0.59) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL16264464 | 0.79 | KMT2A (0.46) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL3044354 | 0.77 | — | — | |
| SCHEMBL27899866 | 0.76 | MEN1 (0.59) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL225275 | 0.75 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL27998679 | 0.75 | MAPK8 (0.48) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL4144275 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL27780484 | 0.74 | KMT2A (0.62) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL17147852 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331634-B1 | FUNGICIDES | MITSUI CHEMICALS, INC. (JP) | 2001-12-18 | — | — | US | disclosed |
| US-6331639-B2 | BY REACTING A 3-((ALKYL, ALKOXY, PHENYL OR HETEROARYL)CARBONYLAMINO)THIOPHENE WITH A KETONE IN THE PRESENCE OF AN ACID AND REDUCING THE REACTION MIXTURE; AGRICULTURAL FUNGICIDES | MITSUI CHEMICALS, INC. (JP) | 2001-12-18 | — | — | US | disclosed |
| US-20010023295-A1 | Process for preparing 2-alkyl-3-aminothiophene derivative and 3-aminothiophene derivative | KATSUTA HIROYUKI (JP) | 2001-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010023295-A1 | Process for preparing 2-alkyl-3-aminothiophene derivative and 3-aminothiophene derivative | SULT1E1, CYP4B1, CYP3A4 | ALDH1A1 322/4885MEN1 1390/4885KMT2A 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.