Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 15/20 | 0.62 |
| ▸ | MEP1A | Q16819 | 3/20 | 0.62 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405810 | 0.92 | MEP1B (0.72) | MEP1BMEP1AFOLH1PTPN1 | |
| SCHEMBL7562335 | 0.83 | AKR1B1 (0.46) | MEP1BMEP1A | |
| SCHEMBL11811255 | 0.82 | MEP1B (0.72) | MEP1BMEP1AFOLH1PTPN1 | |
| SCHEMBL2284795 | 0.81 | TDP1 (0.56) | MEP1B | |
| SCHEMBL7759713 | 0.81 | MEP1B (0.51) | MEP1BMEP1APTPN1 | |
| SCHEMBL5639050 | 0.81 | MEP1B (0.61) | MEP1BMEP1AFOLH1PTPN1 | |
| SCHEMBL6674551 | 0.81 | OPRK1 (0.55) | MEP1BMEP1A | |
| SCHEMBL4407864 | 0.80 | MEP1B (0.65) | MEP1BMEP1AFOLH1PTPN1 | |
| SCHEMBL7564337 | 0.80 | TDP1 (0.58) | — | |
| SCHEMBL2799777 | 0.79 | TDP1 (0.52) | MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163247-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING METAL COMPLEXES | ANORMED INC. (CA) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000056743-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING METAL COMPLEXES | ANORMED INC. (CA) | 2000-09-28 | — | — | WO | disclosed |