Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11321098 | 0.95 | AKR1C3 (0.51) | AKR1C3AKR1C2PPARGPPARAAKR1C1 | |
| SCHEMBL11316020 | 0.94 | AKR1C3 (0.50) | AKR1C3AKR1C2PPARGPPARAAKR1C1 | |
| SCHEMBL2545036 | 0.94 | AKR1C3 (0.50) | AKR1C3AKR1C2PPARGPPARAAKR1C1 | |
| SCHEMBL11319751 | 0.94 | AKR1C3 (0.50) | AKR1C3AKR1C2PPARGPPARAAKR1C1 | |
| SCHEMBL2536993 | 0.94 | AKR1C3 (0.50) | AKR1C3AKR1C2PPARGPPARAAKR1C1 | |
| SCHEMBL11701561 | 0.91 | PPARG (0.57) | AKR1C3AKR1C2PPARGPPARAAKR1C1 | |
| SCHEMBL19612759 | 0.87 | UGT2B7 (0.44) | AKR1C3AKR1C2PPARGPPARAAKR1C1 | |
| SCHEMBL11692258 | 0.85 | AKR1B1 (0.62) | AKR1C3AKR1C2PPARGPPARAAKR1C1 | |
| SCHEMBL2318137 | 0.84 | AKR1C3 (0.69) | AKR1C3AKR1C2PPARGPPARAAKR1C1 | |
| SCHEMBL6898435 | 0.84 | AKR1C3 (0.48) | AKR1C3AKR1C2PPARGPPARAAKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323275-B2 | HAVING A LOWERED ADHESION TO THE SKIN | TOAGOSEI CO., LTD. (JP) | 2001-11-27 | — | — | US | claimed |
| US-6323275-B2 | HAVING A LOWERED ADHESION TO THE SKIN | TOAGOSEI CO., LTD. (JP) | 2001-11-27 | — | — | US | disclosed |
| US-20010004655-A1 | CYANOACRYLATE ADHESIVE COMPOSITION | TOAGOSEI CO., LTD. (JP) | 2001-06-21 | — | — | US | disclosed |