Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11316020 | 1.00 | AKR1C3 (0.50) | AKR1C3AKR1C2PPARGPPARAAKR1C1 | |
| SCHEMBL11319751 | 1.00 | AKR1C3 (0.50) | AKR1C3AKR1C2PPARGPPARAAKR1C1 | |
| SCHEMBL2545036 | 1.00 | AKR1C3 (0.50) | AKR1C3AKR1C2PPARGPPARAAKR1C1 | |
| SCHEMBL11321098 | 0.99 | AKR1C3 (0.51) | AKR1C3AKR1C2PPARGPPARAAKR1C1 | |
| SCHEMBL7799567 | 0.94 | AKR1C3 (0.52) | AKR1C3AKR1C2PPARGPPARAAKR1C1 | |
| SCHEMBL11701561 | 0.88 | PPARG (0.57) | AKR1C3AKR1C2PPARGPPARAAKR1C1 | |
| SCHEMBL9062912 | 0.87 | HDAC1 (0.47) | AKR1C3AKR1C2PPARGPPARAHDAC1 | |
| SCHEMBL6898435 | 0.84 | AKR1C3 (0.48) | AKR1C3AKR1C2PPARGPPARAAKR1C1 | |
| SCHEMBL2552649 | 0.83 | TBXAS1 (0.54) | LMNACNR2POLB | |
| SCHEMBL2550963 | 0.83 | TBXAS1 (0.54) | LMNACNR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3206723-A1 | BIOLOGICAL INDICATOR | American Sterilizer Company (US) | 2017-08-23 | — | — | EP | claimed |
| US-9701968-B2 | Biological indicator | AMERICAN STERILIZER COMPANY (US) | 2017-07-11 | — | — | US | claimed |
| US-20160312263-A1 | BIOLOGICAL INDICATOR | AMERICAN STERILIZER CO (US) | 2016-10-27 | — | — | US | claimed |
| WO-2016060714-A1 | BIOLOGICAL INDICATOR | AMERICAN STERILIZER COMPANY (US) | 2016-04-21 | — | — | WO | claimed |
| US-20160102335-A1 | BIOLOGICAL INDICATOR | AMERICAN STERILIZER COMPANY | 2016-04-14 | — | — | US | claimed |
| US-8507248-B2 | Genetically engineered biological indicator | AMERICAN STERILIZER COMPANY (US) | 2013-08-13 | — | — | US | claimed |
| US-8173389-B2 | Process for determining the effectiveness of a sterilization | AMERICAN STERILIZER COMPANY (US) | 2012-05-08 | — | — | US | claimed |
| US-20100267044-A1 | GENETICALLY ENGINEERED BIOLOGICAL INDICATOR | FRANCISKOVICH PHILLIP P | 2010-10-21 | — | — | US | claimed |
| EP-2084294-A2 | STERILIZATION INDICATOR | American Sterilizer Company (US) | 2009-08-05 | — | — | EP | claimed |
| EP-2084293-A2 | GENETICALLY ENGINEERED BIOLOGICAL INDICATOR | American Sterilizer Company (US) | 2009-08-05 | — | — | EP | claimed |
| US-20090117603-A1 | STERILIZATION INDICATOR | FRANCISKOVICH PHILLIP P | 2009-05-07 | — | — | US | claimed |
| WO-2008082728-A2 | STERILIZATION INDICATOR | AMERICAN STERILIZER COMPANY (US) | 2008-07-10 | — | — | WO | claimed |
| WO-2008079469-A2 | GENETICALLY ENGINEERED BIOLOGICAL INDICATOR | AMERICAN STERILIZER COMPANY (US) | 2008-07-03 | — | — | WO | claimed |
| US-20080070231-A1 | Reporter genes taken up by microorganism, and repressor gene inhibits expression | AMERICAN STERILIZER COMPANY | 2008-03-20 | — | — | US | claimed |
| US-20080070272-A1 | STERILIZATION INDICATOR | AMERICAN STERILIZER COMPANY | 2008-03-20 | — | — | US | claimed |
| US-10619181-B2 | Method for detecting a Shigella or Cronobacter microorganism | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2020-04-14 | — | — | US | disclosed |
| US-10301631-B2 | Biological indicator | AMERICAN STERILIZER COMPANY (US) | 2019-05-28 | — | — | US | disclosed |
| US-5223401-A | Colorimetric analysis; substrate system producing detectable enzyme-modified product | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-06-29 | — | — | US | disclosed |
| US-5073488-A | Using active enzyme | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0371682-A2 | Rapid method for determining efficacy of a sterilization cycle and rapid read-out biological indicator | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-06-06 | — | — | EP | disclosed |