Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 20/20 | 0.56 |
| ▸ | RXRG | P48443 | 11/20 | 0.56 |
| ▸ | RXRB | P28702 | 10/20 | 0.56 |
| ▸ | RARA | P10276 | 2/20 | 0.56 |
| ▸ | RARB | P10826 | 2/20 | 0.56 |
| ▸ | RARG | P13631 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086450 | 0.90 | CYP3A4 (0.47) | RXRARXRGRXRBRARARARB | |
| SCHEMBL7802063 | 0.89 | RXRA (0.54) | RXRARXRGRXRBRARARARB | |
| SCHEMBL8092497 | 0.80 | CYP26A1 (0.70) | RXRARXRGRXRBRARARARB | |
| SCHEMBL7801863 | 0.79 | RXRA (0.48) | RXRARXRGRXRBRARARARB | |
| SCHEMBL8093197 | 0.79 | CYP3A4 (0.54) | RXRARXRGRXRBRARARARB | |
| SCHEMBL7799981 | 0.79 | RXRA (0.51) | RXRARXRGRXRBRARARARB | |
| SCHEMBL16926723 | 0.78 | RXRA (0.72) | RXRARXRGRXRBRARARARB | |
| SCHEMBL7803974 | 0.78 | CYP26A1 (0.55) | RXRARXRGRXRBRARARARB | |
| SCHEMBL28518784 | 0.75 | RXRA (0.70) | RXRARXRGRXRBRARARARB | |
| SCHEMBL7810742 | 0.74 | CYP26A1 (0.64) | RXRARXRGRXRBRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882033-B1 | BENZOFURAN-ACRYLIC ACID DERIVATIVES AND THEIR USE AS MODULATORS OF RXRS OR RARS RECEPTORS | CT INTERNAT DE RECH S (FR) | 2001-08-16 | — | — | EP | disclosed |
| EP-0882033-A1 | BENZOFURAN-ACRYLIC ACID DERIVATIVES AND THEIR USE AS MODULATORS OF RXRS OR RARS RECEPTORS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1998-12-09 | — | — | EP | disclosed |
| WO-1998024778-A1 | BENZOFURAN-ACRYLIC ACID DERIVATIVES AND THEIR USE AS MODULATORS OF RXRS OR RARS RECEPTORS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-06-11 | — | — | WO | disclosed |