Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.35 |
| ▸ | CYP3A5 | P20815 | 4/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3295045 | 1.00 | FNTA (0.38) | FNTAFNTBCYP3A4CYP3A5CYP19A1 | |
| SCHEMBL3296789 | 0.90 | CYP3A4 (0.36) | FNTAFNTBCYP3A4CYP3A5CYP19A1 | |
| SCHEMBL3294234 | 0.89 | CYP3A4 (0.49) | FNTAFNTBCYP3A4CYP3A5CYP19A1 | |
| SCHEMBL3296486 | 0.87 | CYP3A4 (0.35) | CYP3A4CYP3A5SLC6A9GMNNTP53 | |
| SCHEMBL3294295 | 0.85 | ACHE (0.36) | — | |
| SCHEMBL3297656 | 0.80 | SMN1; SMN2 (0.36) | CYP3A4CYP19A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3296939 | 0.78 | AGTR2 (0.36) | — | |
| SCHEMBL3296344 | 0.78 | PSEN1 (0.38) | CYP3A4CYP3A5CYP19A1CYP2D6SLC6A9 | |
| SCHEMBL3296451 | 0.77 | CYP3A4 (0.41) | FNTAFNTBCYP3A4CYP3A5CYP19A1 | |
| SCHEMBL3299776 | 0.75 | AGTR2 (0.37) | CYP3A4CYP19A1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010027193-A1 | Azetidine derivatives, their preparation and pharmaceutical compositions containing them | AVENTIS PHARMA S.A. (FR) | 2001-10-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010027193-A1 | Azetidine derivatives, their preparation and pharmaceutical compositions containing them | ALK, CYP2C9, CBR1 | FNTA 4462/4885FNTB 4588/4885CYP3A4 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.