Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 7/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792891 | 0.89 | TDP1 (0.57) | TDP1MAOBIDO1MEN1KMT2A | |
| SCHEMBL19497462 | 0.83 | ALDH1A1 (0.49) | TAAR1TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL7800146 | 0.79 | TAAR1 (0.65) | TAAR1TDP1MAOB | |
| SCHEMBL4743206 | 0.78 | ALDH1A1 (0.50) | TDP1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL7801505 | 0.78 | TAAR1 (0.57) | TAAR1TDP1ALDH1A1 | |
| SCHEMBL7800221 | 0.77 | TDP1 (0.53) | TAAR1TDP1MAOBIDO1MEN1 | |
| SCHEMBL19497328 | 0.76 | MEN1 (0.47) | TAAR1TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL4634 | 0.75 | TAAR1 (1.00) | TAAR1MAOBIDO1 | |
| SCHEMBL14102978 | 0.74 | NPC1 (0.61) | TDP1MAOBMEN1KMT2AALDH1A1 | |
| Lysine SCHEMBL7798368 | 0.74 | TDP1 (0.40) | TDP1IDO1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |