Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7800514 | 0.89 | TAAR1 (0.57) | TDP1MAOBALDH1A1MAPTRAB9A | |
| SCHEMBL7800221 | 0.88 | TDP1 (0.53) | TDP1MAOBALDH1A1MAPTMEN1 | |
| SCHEMBL4743206 | 0.80 | ALDH1A1 (0.50) | TDP1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL5508681 | 0.79 | MAOB (0.63) | TDP1MAOBIDO1LMNA | |
| SCHEMBL19497462 | 0.79 | ALDH1A1 (0.49) | TDP1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL27717239 | 0.78 | TDP1 (0.55) | TDP1MEN1KMT2ALMNA | |
| SCHEMBL14102978 | 0.77 | NPC1 (0.61) | TDP1MAOBALDH1A1RAB9AMEN1 | |
| SCHEMBL1236491 | 0.76 | ALDH1A1 (0.66) | TDP1ALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL29889164 | 0.76 | TDP1 (1.00) | TDP1ALDH1A1MAPTRAB9ATP53 | |
| SCHEMBL95435 | 0.76 | TDP1 (1.00) | TDP1ALDH1A1MAPTRAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |