Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871689 | 0.85 | PRKCI (0.39) | PRKCIPCSK9ALDH1A1CYP2A6CYP2A13 | |
| SCHEMBL6136899 | 0.82 | PDE10A (0.46) | PRKCIPCSK9ALDH1A1CYP2A6CYP2A13 | |
| SCHEMBL14399953 | 0.82 | DYRK3 (0.42) | PCSK9ALDH1A1CDK5DYRK1ADYRK1B | |
| SCHEMBL5705031 | 0.80 | TSHR (0.42) | PRKCIPCSK9ALDH1A1CYP2A6CYP2A13 | |
| SCHEMBL7812485 | 0.80 | PRKCI (0.35) | PRKCIPCSK9ALDH1A1CYP2A6CYP2A13 | |
| SCHEMBL7808589 | 0.80 | HTR1A (0.35) | PRKCIPCSK9ALDH1A1CYP2A6CYP2A13 | |
| SCHEMBL7805929 | 0.80 | PCSK9 (0.33) | PCSK9ALDH1A1CYP2A6CYP2A13BRD4 | |
| SCHEMBL7806005 | 0.80 | ALDH1A1 (0.40) | PCSK9ALDH1A1CYP2A6CYP2A13EPHX2 | |
| SCHEMBL6374395 | 0.79 | ALDH1A1 (0.48) | PCSK9ALDH1A1CYP2A6CYP2A13NPC1 | |
| SCHEMBL7800649 | 0.76 | CYP3A4 (0.45) | PCSK9ALDH1A1CYP2A6CYP2A13TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | claimed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | claimed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | claimed |
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |