Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793679 | 0.92 | TSHR (0.64) | TSHRCYP3A4TP53PPARAPPARG | |
| SCHEMBL7801086 | 0.90 | TSHR (0.71) | TSHRCYP3A4TP53PPARAKMT2A | |
| SCHEMBL7802428 | 0.89 | TSHR (0.74) | TSHRCYP3A4TP53PPARAPPARG | |
| SCHEMBL29577774 | 0.88 | TP53 (0.62) | TSHRCYP3A4TP53PPARAPPARG | |
| SCHEMBL655678 | 0.88 | TP53 (0.62) | TSHRCYP3A4TP53PPARAPPARG | |
| SCHEMBL14885541 | 0.82 | PPARA (0.60) | TSHRPPARAKMT2APPARGPLA2G4B | |
| SCHEMBL993788 | 0.82 | TSHR (0.77) | TSHRCYP3A4TP53KMT2AMAOB | |
| SCHEMBL217079 | 0.81 | CYP3A4 (0.56) | TSHRCYP3A4TP53KMT2AMAOB | |
| SCHEMBL4563082 | 0.81 | ALOX15 (0.55) | TSHRCYP3A4TP53KMT2AALDH1A1 | |
| SCHEMBL11782480 | 0.80 | PPARA (0.51) | PPARAKMT2APPARGPLA2G4BMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900255-B1 | DONOR-SUBSTITUTED OXINDIGO DERIVATIVES AND THEIR USE AS COLOURANTS | CIBA SC HOLDING AG (CH) | 2001-12-19 | — | — | EP | disclosed |
| US-6156914-A | Donor-substituted oxindigo derivatives and their use as colorants | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-12-05 | — | — | US | disclosed |
| EP-0900255-A1 | DONOR-SUBSTITUTED OXINDIGO DERIVATIVES AND THEIR USE AS COLOURANTS | Ciba SC Holding AG (CH) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041176-A1 | DONOR-SUBSTITUTED OXINDIGO DERIVATIVES AND THEIR USE AS COLOURANTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1997-11-06 | — | — | WO | disclosed |