Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.58 |
| ▸ | MAOB | P27338 | 5/20 | 0.56 |
| ▸ | LAP3 | P28838 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27312933 | 0.88 | MAOB (0.60) | LTA4HMAOBLAP3ALOX5PTGS1 | |
| SCHEMBL7438290 | 0.88 | SLC7A5 (0.56) | LTA4HLAP3PTGS1 | |
| SCHEMBL7269254 | 0.88 | SLC7A5 (0.56) | LTA4HLAP3PTGS1 | |
| Hydrochloric Acid SCHEMBL1126065 | 0.87 | SLC7A5 (0.54) | LTA4HLAP3PTGS1 | |
| Hydrochloric Acid SCHEMBL6161681 | 0.87 | SLC7A5 (0.54) | LTA4HLAP3PTGS1 | |
| Trifluoroacetic Acid SCHEMBL2496694 | 0.83 | MAOB (0.54) | LTA4HMAOBLAP3ALOX5PTGS1 | |
| SCHEMBL17484675 | 0.83 | LTA4H (0.64) | LTA4HMAOBLAP3ALOX5PTGS1 | |
| SCHEMBL2603686 | 0.83 | LTA4H (0.64) | LTA4HMAOBLAP3ALOX5PTGS1 | |
| SCHEMBL14559932 | 0.83 | LTA4H (0.64) | LTA4HMAOBLAP3ALOX5PTGS1 | |
| Trifluoroacetic Acid SCHEMBL9725806 | 0.82 | ALPI (0.49) | LTA4HLAP3PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721449-B1 | INHIBITORS OF BETA-AMYLOID PROTEIN PRODUCTION | MERRELL PHARMA INC (US) | 2001-12-19 | — | — | EP | disclosed |
| US-5977074-A | THERAPY FOR ALZHEIMER'S DISEASE | MERRELL PHARMACEUTICALS, INC. (US) | 1999-11-02 | — | — | US | disclosed |