Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | LAP3 | P28838 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269254 | 1.00 | SLC7A5 (0.56) | SLC7A5ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL6161681 | 0.98 | SLC7A5 (0.54) | SLC7A5ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL1126065 | 0.98 | SLC7A5 (0.54) | SLC7A5ALPIPKMPTGS1XIAP | |
| Trifluoroacetic Acid SCHEMBL9725806 | 0.93 | ALPI (0.49) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7801253 | 0.88 | LTA4H (0.58) | PTGS1LAP3LTA4H | |
| SCHEMBL9248667 | 0.85 | SLC7A5 (0.58) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7032300 | 0.84 | LNPEP (0.45) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL5885156 | 0.83 | LTA4H (0.52) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7842354 | 0.83 | FAAH (0.47) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL30959049 | 0.83 | ALPI (0.63) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718585-B2 | Bis-cyclic guanidines as antibacterial agents | UNIVERSITY OF SOUTH FLORIDA (US) | 2023-08-08 | — | — | US | disclosed |
| US-11718585-B2 | Bis-cyclic guanidines as antibacterial agents | UNIVERSITY OF SOUTH FLORIDA (US) | 2023-08-08 | — | — | US | disclosed |
| US-20220119352-A1 | BIS-CYCLIC GUANIDINES AS ANTIBACTERIAL AGENTS | NATIONAL SCIENCE FOUNDATION | 2022-04-21 | — | — | US | disclosed |
| US-11214550-B2 | Bis-cyclic guanidines as antibacterial agents | UNIVERSITY OF SOUTH FLORIDA (US) | 2022-01-04 | — | — | US | disclosed |
| US-20200231572-A1 | NOVEL BIS-CYCLIC GUANIDINES AS ANTIBACTERIAL AGENTS | NATIONAL SCIENCE FOUNDATION | 2020-07-23 | — | — | US | disclosed |
| WO-1994019329-A1 | SUBSTITUTED CYCLIC CARBONYLS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-09-01 | — | — | WO | disclosed |
| EP-0607334-A1 | CYCLIC UREAS AND ANALOGUES USEFUL AS RETROVIRAL PROTEASE INHIBITIORS. | DU PONT MERCK PHARMA (US) | 1994-07-27 | — | — | EP | disclosed |
| WO-1993007128-A1 | CYCLIC UREAS AND ANALOGUES USEFUL AS RETROVIRAL PROTEASE INHIBITIORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-04-15 | — | — | WO | disclosed |
| US-5106835-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119352-A1 | BIS-CYCLIC GUANIDINES AS ANTIBACTERIAL AGENTS | GMPS, CGAS, GDA | SLC7A5 2627/4885ALPI 2554/4885PKM 3888/4885 |
| US-11718585-B2 | Bis-cyclic guanidines as antibacterial agents | GMPS, CGAS, GDA | SLC7A5 2627/4885ALPI 2554/4885PKM 3888/4885 |
| US-11214550-B2 | Bis-cyclic guanidines as antibacterial agents | GMPS, CGAS, GDA | SLC7A5 2627/4885ALPI 2554/4885PKM 3888/4885 |
| US-20200231572-A1 | NOVEL BIS-CYCLIC GUANIDINES AS ANTIBACTERIAL AGENTS | GMPS, CGAS, GDA | SLC7A5 2376/4885ALPI 3046/4885PKM 3938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.