Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylacetic Acid SCHEMBL7801510 | 1.00 | ENPP2 (0.39) | ENPP2DRD2DRD4ABCC4LMNA | |
| Lysine SCHEMBL7800559 | 0.97 | ENPP2 (0.39) | ENPP2DRD2DRD4ABCC4LMNA | |
| Lysine SCHEMBL8041240 | 0.97 | ENPP2 (0.39) | ENPP2DRD2DRD4ABCC4LMNA | |
| Lysine SCHEMBL7800562 | 0.97 | ENPP2 (0.39) | ENPP2DRD2DRD4ABCC4LMNA | |
| Ornithine SCHEMBL7793125 | 0.93 | GRIK1 (0.40) | DRD2DRD4GRIN1GRIN2AKMT2A | |
| Ornithine Aketoglutarate SCHEMBL7793129 | 0.93 | GRIK1 (0.40) | DRD2DRD4GRIN1GRIN2AKMT2A | |
| Ornithine SCHEMBL7800251 | 0.92 | GRIK1 (0.38) | DRD2DRD4GRIN1GRIN2AKMT2A | |
| Ornithine SCHEMBL7792272 | 0.92 | GRIK1 (0.39) | DRD2DRD4GRIN1GRIN2AKMT2A | |
| Ornithine SCHEMBL7801718 | 0.91 | GRIK1 (0.37) | DRD2DRD4GRIN1GRIN2AGRIK1 | |
| Ornithine Aketoglutarate SCHEMBL7801714 | 0.91 | GRIK1 (0.37) | DRD2DRD4GRIN1GRIN2AGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |