Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.55 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 5/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265172 | 0.88 | MAOB (0.56) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL8350056 | 0.85 | CA1 (0.54) | SCN9APTGES2CA12CA1CA2 | |
| SCHEMBL7112362 | 0.84 | F10 (0.51) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL22588242 | 0.84 | SCN9A (0.53) | SCN9APTGES2CA12CA1CA2 | |
| SCHEMBL48885 | 0.83 | CA2 (0.52) | SCN9ACA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL6066493 | 0.83 | CA1 (0.52) | SCN9ACA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL6399557 | 0.81 | CA2 (0.50) | SCN9ACA12CA1CA2CA9 | |
| Methane SCHEMBL27503773 | 0.81 | CA2 (0.50) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL27842438 | 0.81 | CA1 (0.54) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL7261137 | 0.79 | SCN9A (0.55) | SCN9ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903339-B1 | Biphenylsulfonylcyanamides, process for their preparation and their use as medicaments | AVENTIS PHARMA GMBH (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-5968978-A | ANTIARRYTHMIA AGENTS, ANTIISCHEMIC AGENTS, INHIBIT PROLIFERATION OF CELLS | HOECHST MARION ROUSSEL DEUTSCHLAND (DE) | 1999-10-19 | — | — | US | disclosed |
| EP-0903339-A2 | Biphenylsulfonylcyanamides, process for their preparation and their use as medicaments | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-03-24 | — | — | EP | disclosed |