SCHEMBL48885

SCHEMBL48885

NS(=O)(=O)c1ccccc1-c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 8/20 0.52
CA1 P00915 7/20 0.52
CA9 Q16790 7/20 0.52
CA12 O43570 6/20 0.52
CA6 P23280 4/20 0.52
CA4 P22748 3/20 0.52
CA5A P35218 3/20 0.52
CA7 P43166 3/20 0.52
CA5B Q9Y2D0 3/20 0.52
CA14 Q9ULX7 2/20 0.52
CYP2C9 P11712 1/20 0.52
SCN9A Q15858 2/20 0.49
ALOX5AP P20292 2/20 0.46
FEN1 P39748 2/20 0.46
CA3 P07451 1/20 0.46
PLA2G7 Q13093 1/20 0.46
CA13 Q8N1Q1 1/20 0.46
F10 P00742 2/20 0.46
PTGS2 P35354 3/20 0.46
PTGS1 P23219 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6399557 0.98 CA2 (0.50) CA2CA1CA9CA12CA6
Methane SCHEMBL27503773 0.98 CA2 (0.50) CA2CA1CA9CA12CA6
SCHEMBL27842438 0.93 CA1 (0.54) CA2CA1CA9CA12CA6
SCHEMBL8350056 0.93 CA1 (0.54) CA2CA1CA9CA12CA6
Trimethylammonium SCHEMBL27979852 0.92 CA2 (0.45) CA2CA1CA9CA12CA6
SCHEMBL8659843 0.91 CA2 (0.48) CA2CA1CA9CA12CA6
Formic Acid SCHEMBL6028133 0.90 CASP1 (0.49) CA2CA1CA9CA12CA6
Acetic Acid SCHEMBL6695169 0.90 SCN9A (0.50) CA2CA1CA9CA12CA6
Trifluoroacetic Acid SCHEMBL15924604 0.86 PRSS1 (0.55) SCN9AF10
SCHEMBL1080972 0.85 CA2 (0.61) CA2CA1CA9CA12CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 986 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219810-A Ionic polymer and preparation method and application thereof 佛山绿动氢能科技有限公司 2024-12-31 CN claimed
WO-2024149712-A1 SELECTIVE ANGIOTENSIN II COMPOUNDS VICORE PHARMA AB (SE) 2024-07-18 WO claimed
CN-116675626-A Preparation method of N-phenyl-N- [ (trichloromethyl) thio ] benzenesulfonamide 蔚林新材料科技股份有限公司 2023-09-01 CN claimed
CN-113527152-B Biphenyl sulfonamide compound and method for controlling crop pests by using same 西北农林科技大学 2023-07-28 CN claimed
CN-116285353-A Wear-resistant impact-resistant PPS/THV hybrid fiber alloy material and preparation method thereof 青岛科技大学 2023-06-23 CN claimed
CN-113527152-A Biphenylsulfonamide compound and method for preventing and treating crop pests by using same 西北农林科技大学 2021-10-22 CN claimed
CN-108117553-B Alkynes phenyl benzenesulfonamides class selectivity ZAK inhibitor and its application 暨南大学 2019-08-16 CN claimed
CN-109715629-A AZA-INDAZOLE COMPOUNDS FOR USE IN TENDON AND/OR LIGAMENT INJURIES 诺华股份有限公司 2019-05-03 CN claimed
CN-107033039-B A kind of synthetic method of his key intermediate of anti-tumor drug Baily department 东南大学 2019-04-30 CN claimed
CN-109414503-A The pharmaceuticals for the treatment of for multiple sclerosis 日本化学药品株式会社 2019-03-01 CN claimed
JP-H09509925-A 1997-10-07 JP claimed
WO-1997029747-A1 METHODS FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES BRISTOL-MYERS SQUIBB COMPANY (US) 1997-08-21 WO claimed
EP-0748314-A1 NOVEL TETRASUBSTITUTED IMIDAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, RESULTING NOVEL INTERMEDIATES, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME ROUSSEL UCLAF (FR) 1996-12-18 EP claimed
EP-0699191-A1 SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN TEXAS BIOTECHNOLOGY CORPORATION (US) 1996-03-06 EP claimed
WO-1995023791-A1 NOVEL TETRASUBSTITUTED IMIDAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, RESULTING NOVEL INTERMEDIATES, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME ROUSSEL UCLAF (FR) 1995-09-08 WO claimed
EP-0638572-A1 Bicyclic derivatives of imidazole, process for their preparation, intermediates; their application as medicaments and pharmaceutical compostions containing them ROUSSEL UCLAF (FR) 1995-02-15 EP claimed
WO-1994027979-A1 SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN IMMUNOPHARMACEUTICS, INC. (US) 1994-12-08 WO claimed
US-4612385-A Process for the preparation of phenyl N-(2-biphenylylsulfonyl) carbamate NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-09-16 US claimed
EP-0185227-A2 Process for the preparation of phenyl-N-(2-biphenylylsulfonyl) carbamate NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-06-25 EP claimed
EP-0158248-A2 Process for the preparation of biphenylsulfonyl urea derivatives, their intermediates and process for the preparation of the intermediates NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-10-16 EP claimed