Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801797 | 1.00 | LMNA (0.38) | LMNATDP1L3MBTL1CYP11B1CYP11B2 | |
| SCHEMBL7804547 | 0.88 | LMNA (0.42) | LMNATDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7804550 | 0.88 | LMNA (0.42) | LMNATDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7803883 | 0.87 | KMT2A (0.37) | KMT2AALDH1A1CYP1A2CYP2C9MEN1 | |
| SCHEMBL7801802 | 0.87 | LMNA (0.39) | LMNATDP1L3MBTL1CYP11B1CYP11B2 | |
| SCHEMBL7801805 | 0.87 | LMNA (0.39) | LMNATDP1L3MBTL1CYP11B1CYP11B2 | |
| SCHEMBL7805468 | 0.87 | ABL1 (0.46) | LMNATDP1CYP11B1CYP11B2KMT2A | |
| SCHEMBL7805464 | 0.87 | ABL1 (0.46) | LMNATDP1CYP11B1CYP11B2KMT2A | |
| SCHEMBL7801819 | 0.86 | ALDH1A1 (0.42) | LMNATDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7803839 | 0.86 | ALDH1A1 (0.49) | LMNATDP1L3MBTL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097117-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000003975-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2000-01-27 | — | — | WO | disclosed |