Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.52 |
| ▸ | ABAT | P80404 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | APP | P05067 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CA3 | P07451 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | CA5A | P35218 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702901 | 0.80 | ALDH5A1 (0.48) | ALDH5A1ABATALDH1A1MAPTAPP | |
| SCHEMBL363138 | 0.77 | ALDH5A1 (0.50) | ALDH5A1ABATALDH1A1MAPTAPP | |
| SCHEMBL7702823 | 0.77 | ALDH5A1 (0.44) | ALDH5A1ABATALDH1A1MAPTAPP | |
| SCHEMBL1253743 | 0.76 | ALDH5A1 (0.55) | ALDH5A1ABATALDH1A1MAPTAPP | |
| SCHEMBL1682354 | 0.76 | ALDH5A1 (0.55) | ALDH5A1ABATALDH1A1MAPTAPP | |
| SCHEMBL3255611 | 0.75 | APP (0.52) | ALDH1A1MAPTAPPKDM4EKMT2A | |
| SCHEMBL4758209 | 0.74 | ABAT (0.52) | ALDH5A1ABATALDH1A1MAPTAPP | |
| SCHEMBL11144431 | 0.74 | APP (0.37) | ALDH1A1APPCYP3A4 | |
| SCHEMBL11140842 | 0.74 | CYP2A6 (0.42) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL7795364 | 0.74 | CYP2A6 (0.52) | MAPTKDM4EKMT2AMEN1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |