SCHEMBL363138

SCHEMBL363138

C=CC[CH]c1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH5A1 P51649 2/20 0.50
ABAT P80404 2/20 0.50
ALDH1A1 P00352 5/20 0.42
MAPT P10636 5/20 0.42
APP P05067 4/20 0.42
KDM4E B2RXH2 4/20 0.40
MAOB P27338 3/20 0.40
MEN1 O00255 3/20 0.40
CA12 O43570 3/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
LMNA P02545 3/20 0.40
CA3 P07451 3/20 0.40
CYP3A4 P08684 3/20 0.40
HPGD P15428 3/20 0.40
CA4 P22748 3/20 0.40
CA5A P35218 3/20 0.40
KMT2A Q03164 3/20 0.40
HIF1A Q16665 3/20 0.40
CA9 Q16790 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7801924 0.77 ALDH5A1 (0.52) ALDH5A1ABATALDH1A1MAPTAPP
SCHEMBL9247763 0.76 APP (0.50) ALDH1A1MAPTAPPKDM4EMAOB
SCHEMBL9247768 0.76 APP (0.50) ALDH1A1MAPTAPPKDM4EMAOB
SCHEMBL3701501 0.75 CYP2A6 (0.50) ALDH1A1MAPTKDM4ECA1CYP3A4
SCHEMBL7428108 0.75 NFE2L2 (0.41) ALDH1A1MAPTAPPSMN1; SMN2GAA
SCHEMBL1253743 0.74 ALDH5A1 (0.55) ALDH5A1ABATALDH1A1MAPTAPP
SCHEMBL1682354 0.74 ALDH5A1 (0.55) ALDH5A1ABATALDH1A1MAPTAPP
SCHEMBL87669 0.74 ALDH1A1 (0.52) ALDH1A1MAOBMEN1LMNAKMT2A
SCHEMBL7702901 0.73 ALDH5A1 (0.48) ALDH5A1ABATALDH1A1MAPTAPP
4-Vinylphenol SCHEMBL170622 0.73 ALDH1A1 (0.69) ALDH5A1ABATALDH1A1MAPTAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090118198-A1 NOVEL PEPTIDE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS FOR TREATING WOUNDS ZULA DIAGNOSTICS AB (SE) 2009-05-07 US claimed
EP-2019819-A1 NOVEL PEPTIDE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS FOR TREATING WOUNDS Neobiotics AB (SE) 2009-02-04 EP claimed
WO-2007129952-A1 NOVEL PEPTIDE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS FOR TREATING WOUNDS NEOBIOTICS AB (SE) 2007-11-15 WO claimed
US-8097582-B2 Peptide derivatives useful as antimicrobial agents and for treating wounds NEOBIOTICS AB (SE) 2012-01-17 US disclosed
US-20090118198-A1 NOVEL PEPTIDE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS FOR TREATING WOUNDS ZULA DIAGNOSTICS AB (SE) 2009-05-07 US disclosed
EP-2019819-A1 NOVEL PEPTIDE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS FOR TREATING WOUNDS Neobiotics AB (SE) 2009-02-04 EP disclosed
WO-2007129952-A1 NOVEL PEPTIDE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS FOR TREATING WOUNDS NEOBIOTICS AB (SE) 2007-11-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090118198-A1 NOVEL PEPTIDE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS FOR TREATING WOUNDS VIP, NGLY1, ARG1 ALDH5A1 4361/4885ABAT 2128/4885ALDH1A1 4435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.