Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 9/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801434 | 1.00 | CXCR2 (0.40) | CXCR2CXCR1LMNAALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7804257 | 0.99 | CXCR2 (0.40) | CXCR2CXCR1LMNAALDH1A1GAA | |
| SCHEMBL7802233 | 0.94 | CXCR2 (0.39) | CXCR2CXCR1LMNAALDH1A1GAA | |
| SCHEMBL7801221 | 0.92 | CXCR2 (0.41) | CXCR2CXCR1ALDH1A1GAAMAPKAPK2 | |
| SCHEMBL7801773 | 0.91 | ALDH1A1 (0.49) | CXCR2CXCR1LMNAALDH1A1GAA | |
| SCHEMBL7801488 | 0.91 | ALDH1A1 (0.49) | CXCR2CXCR1LMNAALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7801287 | 0.91 | CXCR2 (0.41) | CXCR2CXCR1ALDH1A1MAPKAPK2CCR6 | |
| Hydrochloric Acid SCHEMBL7805684 | 0.91 | ALDH1A1 (0.48) | CXCR2CXCR1LMNAALDH1A1GAA | |
| SCHEMBL7795412 | 0.90 | CXCR2 (0.40) | CXCR2CXCR1MAPKAPK2CCR6TEAD4 | |
| SCHEMBL7805393 | 0.90 | CXCR2 (0.40) | CXCR2CXCR1MAPKAPK2CCR6TEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | claimed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |