Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.39 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.39 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 4/20 | 0.36 |
| ▸ | TDP2 | O95551 | 3/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720647 | 0.89 | S100A4 (0.40) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL7721584 | 0.79 | S100A4 (0.41) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL7721587 | 0.76 | S100A4 (0.50) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL7716553 | 0.76 | S100A4 (0.49) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL7721589 | 0.72 | S100A4 (0.39) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL7721572 | 0.72 | S100A4 (0.44) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL7719613 | 0.69 | S100A4 (0.50) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL7721606 | 0.69 | S100A4 (0.47) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL7720787 | 0.68 | S100A4 (0.44) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL10505905 | 0.67 | S100A4 (0.58) | S100A4MEN1KMT2ATDP1GUCY1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984010-B1 | Use in hair dyes of quinolin-5,8-diones or quinoxalin-5,8-diones condensed with substituted pyrroles, anilines or indoles | OREAL (FR) | 2001-06-20 | — | — | EP | disclosed |
| EP-0984010-A1 | Use in hair dyes of quinolin-5,8-diones or quinoxalin-5,8-diones condensed with substituted pyrroles, anilines or indoles | L'OREAL (FR) | 2000-03-08 | — | — | EP | disclosed |