Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 18/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7785571 | 0.85 | MAPKAPK2 (0.35) | CXCR2CXCR1 | |
| SCHEMBL7805393 | 0.85 | CXCR2 (0.40) | CXCR2CXCR1CCR6 | |
| SCHEMBL7795412 | 0.85 | CXCR2 (0.40) | CXCR2CXCR1CCR6 | |
| Trifluoroacetic Acid SCHEMBL7804017 | 0.84 | CXCR2 (0.37) | CXCR2CXCR1 | |
| Hydrochloric Acid SCHEMBL7803652 | 0.84 | CXCR2 (0.39) | CXCR2CXCR1CCR6 | |
| Hydrochloric Acid SCHEMBL7795371 | 0.83 | CXCR2 (0.39) | CXCR2CXCR1CCR6 | |
| Hydrochloric Acid SCHEMBL7801936 | 0.82 | MAPKAPK2 (0.41) | CXCR2CXCR1CCR6 | |
| SCHEMBL7801221 | 0.77 | CXCR2 (0.41) | CXCR2CXCR1CCR6 | |
| Hydrochloric Acid SCHEMBL7801287 | 0.76 | CXCR2 (0.41) | CXCR2CXCR1CCR6 | |
| SCHEMBL7801434 | 0.76 | CXCR2 (0.40) | CXCR2CXCR1CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |