Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DDX3X | O00571 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7802542 | 1.00 | TSHR (0.56) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL7804309 | 0.96 | TSHR (0.57) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL7804311 | 0.96 | TSHR (0.57) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL7801772 | 0.95 | ALDH1A1 (0.58) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL7801774 | 0.95 | ALDH1A1 (0.58) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL7806139 | 0.89 | PTGS2 (0.44) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL7806138 | 0.89 | PTGS2 (0.44) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL7755657 | 0.87 | TSHR (0.43) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL7755654 | 0.87 | TSHR (0.43) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL7802552 | 0.84 | KDM4E (0.51) | TSHRL3MBTL1TDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097117-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000003975-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2000-01-27 | — | — | WO | disclosed |