Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL7798612 | 0.91 | MAOB (0.51) | MAOBTAAR1NPC1RAB9ATDP1 | |
| SCHEMBL7800391 | 0.89 | TAAR1 (0.59) | MAOBTAAR1NPC1RAB9ATDP1 | |
| SCHEMBL7801502 | 0.89 | TAAR1 (0.55) | MAOBTAAR1NPC1RAB9ATDP1 | |
| SCHEMBL7800259 | 0.88 | MAOB (0.58) | MAOBTAAR1NPC1RAB9ATDP1 | |
| Phenethylamine SCHEMBL7800077 | 0.84 | TAAR1 (0.62) | MAOBTAAR1 | |
| Benzoic Acid SCHEMBL8035799 | 0.81 | TAAR1 (0.44) | MAOBTAAR1NPC1RAB9AMEN1 | |
| Benzoic Acid SCHEMBL7800370 | 0.81 | MEN1 (0.53) | MAOBTAAR1NPC1RAB9ATDP1 | |
| SCHEMBL7793185 | 0.81 | RAB9A (0.47) | MAOBNPC1RAB9ATDP1MEN1 | |
| SCHEMBL7800097 | 0.81 | TAAR1 (0.61) | MAOBTAAR1TDP1MEN1KMT2A | |
| Benzoic Acid SCHEMBL7798463 | 0.80 | MAOB (0.49) | MAOBNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |