Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7800391 | 0.92 | TAAR1 (0.59) | TAAR1KDM4EMEN1KMT2AMAOB | |
| Benzoic Acid SCHEMBL7800774 | 0.91 | TAAR1 (0.50) | TAAR1KDM4EMEN1KMT2AACHE | |
| SCHEMBL7802621 | 0.90 | MAOB (0.47) | TAAR1KDM4EMEN1KMT2AMAOB | |
| 4-Methylbenzoic Acid SCHEMBL7792499 | 0.88 | TAAR1 (0.47) | TAAR1KDM4EMEN1KMT2AMAOB | |
| SCHEMBL8035116 | 0.87 | PTGES (0.48) | TAAR1KDM4EMEN1KMT2AMAOB | |
| SCHEMBL7798027 | 0.87 | KDM4E (0.46) | TAAR1KDM4EMEN1KMT2AMAOB | |
| SCHEMBL7801502 | 0.86 | TAAR1 (0.55) | TAAR1MEN1KMT2AMAOBALDH1A1 | |
| Benzoic Acid SCHEMBL7800370 | 0.83 | MEN1 (0.53) | TAAR1KDM4EMEN1KMT2AMAOB | |
| Benzaldehyde SCHEMBL14677731 | 0.82 | TAAR1 (0.71) | TAAR1KDM4EMEN1KMT2AMAOB | |
| Phenethylamine SCHEMBL7801605 | 0.82 | TAAR1 (0.53) | TAAR1MAOBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |