Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Chloro-Benzoic Acid SCHEMBL7802647 | 1.00 | CYP2C9 (0.40) | CYP2C9MEN1KMT2AGAAALDH1A1 | |
| Lysine SCHEMBL7800125 | 0.97 | LTA4H (0.41) | CYP2C9MEN1KMT2AGAAALDH1A1 | |
| Lysine SCHEMBL7800126 | 0.97 | LTA4H (0.41) | CYP2C9MEN1KMT2AGAAALDH1A1 | |
| Ornithine SCHEMBL7801588 | 0.94 | LTA4H (0.42) | CYP2C9MEN1KMT2AGAAALDH1A1 | |
| 4-Chloro-Benzoic Acid SCHEMBL7798514 | 0.92 | MEN1 (0.41) | MEN1KMT2AALDH1A1LMNAHTT | |
| Lysine SCHEMBL7798157 | 0.91 | LTA4H (0.44) | CYP2C9MEN1KMT2AGAAALDH1A1 | |
| Ornithine SCHEMBL7802718 | 0.91 | LTA4H (0.45) | CYP2C9MEN1KMT2AALDH1A1LTA4H | |
| Ornithine Aketoglutarate SCHEMBL7798041 | 0.91 | LTA4H (0.45) | CYP2C9MEN1KMT2AALDH1A1LTA4H | |
| D-Ornithine SCHEMBL7798039 | 0.91 | LTA4H (0.45) | CYP2C9MEN1KMT2AALDH1A1LTA4H | |
| 4-Chloro-Benzoic Acid SCHEMBL7798237 | 0.90 | LTA4H (0.44) | GAAALDH1A1LTA4HPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |