Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.58 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052171 | 1.00 | ADRB1 (0.58) | ADRB1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL31051858 | 0.91 | ADRB1 (0.54) | ADRB1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL31051830 | 0.90 | ADRB1 (0.58) | ADRB1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL31051952 | 0.88 | ADRB1 (0.57) | ADRB1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL31051873 | 0.88 | ADRB1 (0.57) | ADRB1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7853985 | 0.88 | HTR1A (0.55) | ADRB1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL31051798 | 0.87 | HTR1A (0.48) | ADRB1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL31051806 | 0.86 | ADRB1 (0.54) | ADRB1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL31051859 | 0.86 | HTR1A (0.61) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL31052038 | 0.84 | HTR1A (0.43) | ADRB1HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796251-B1 | URACIL DERIVATIVES | BYK GULDEN LOMBERG CHEM FAB (DE) | 2001-10-17 | — | — | EP | disclosed |
| US-6046329-A | Uracil derivatives | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-04-04 | — | — | US | disclosed |
| WO-1996017831-A1 | URACIL DERIVATIVES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-06-13 | — | — | WO | disclosed |