Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828778 | 0.90 | DRD2 (0.53) | DRD2DRD3CYP2D6HTR1ADRD4 | |
| SCHEMBL7802816 | 0.85 | DRD2 (0.49) | DRD2DRD3CYP2D6HTR1ALMNA | |
| SCHEMBL8828524 | 0.84 | DRD2 (0.53) | DRD2DRD3CYP2D6HTR1ALMNA | |
| SCHEMBL6771682 | 0.82 | ADRA1A (0.60) | DRD2DRD3CYP2D6HTR1ALMNA | |
| SCHEMBL7800106 | 0.81 | DRD2 (0.70) | DRD2DRD3CYP2D6HTR1ADRD4 | |
| SCHEMBL2215388 | 0.80 | DRD2 (0.76) | DRD2DRD3CYP2D6HTR1AALDH1A1 | |
| SCHEMBL29395171 | 0.80 | DRD2 (0.76) | DRD2DRD3CYP2D6HTR1AALDH1A1 | |
| SCHEMBL8828610 | 0.80 | DRD2 (0.57) | DRD2DRD3CYP2D6HTR1ADRD4 | |
| SCHEMBL5813861 | 0.79 | ADRA1A (0.68) | DRD2DRD3HTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL11047866 | 0.79 | DRD2 (0.74) | DRD2DRD3HTR1ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796251-B1 | URACIL DERIVATIVES | BYK GULDEN LOMBERG CHEM FAB (DE) | 2001-10-17 | — | — | EP | disclosed |
| US-6046329-A | Uracil derivatives | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-04-04 | — | — | US | disclosed |
| EP-0796251-A1 | URACIL DERIVATIVES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1997-09-24 | — | — | EP | disclosed |
| WO-1996017831-A1 | URACIL DERIVATIVES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-06-13 | — | — | WO | disclosed |