SCHEMBL7802853

SCHEMBL7802853

O=C(O)CCN1C(=O)C2CCCCC2C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.53
ALDH1A1 P00352 5/20 0.50
PKM P14618 1/20 0.50
RAB9A P51151 3/20 0.49
ATM Q13315 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 1/20 0.45
POLB P06746 1/20 0.45
HSD17B10 Q99714 1/20 0.45
KMT2A Q03164 2/20 0.45
HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7806227 1.00 MAPK1 (0.53) MAPK1ALDH1A1PKMRAB9AATM
SCHEMBL7804032 0.89 ATM (0.46) MAPK1ALDH1A1RAB9AATMSMN1; SMN2
SCHEMBL7802034 0.89 ATM (0.46) MAPK1ALDH1A1RAB9AATMSMN1; SMN2
SCHEMBL9157558 0.86 PTGS1 (0.53) MAPK1ALDH1A1ATMSMN1; SMN2KMT2A
SCHEMBL5001199 0.82 ALDH1A1 (0.45) ALDH1A1RAB9AATMSMN1; SMN2L3MBTL1
SCHEMBL17532412 0.81 ALDH1A1 (0.53) ALDH1A1RAB9AATMSMN1; SMN2L3MBTL1
SCHEMBL7796006 0.80 HTT (0.49) ALDH1A1RAB9AATMSMN1; SMN2L3MBTL1
SCHEMBL7804745 0.80 HTT (0.49) ALDH1A1RAB9AATMSMN1; SMN2L3MBTL1
SCHEMBL7290092 0.80 HTT (0.56) ALDH1A1SMN1; SMN2L3MBTL1POLBKMT2A
SCHEMBL5336840 0.80 HTT (0.56) ALDH1A1SMN1; SMN2L3MBTL1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0366041-B2 Imido-percarboxylic acids AUSIMONT SPA (IT) 2001-09-12 EP claimed
EP-0366041-B1 Imido-percarboxylic acids AUSIMONT SPA (IT) 1998-08-05 EP claimed
EP-0366041-A2 Imido-percarboxylic acids AUSIMONT S.r.l. (IT) 1990-05-02 EP claimed