Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802246 | 0.69 | MAPT (0.58) | MAPTHTTKDM4EALDH1A1NPSR1 | |
| SCHEMBL3806352 | 0.66 | MAPT (0.44) | PLA2G7MAPTHTTKDM4EALDH1A1 | |
| SCHEMBL4198025 | 0.66 | MCL1 (0.57) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL12929340 | 0.65 | NPSR1 (0.68) | MAPTHTTALDH1A1NPSR1KMT2A | |
| SCHEMBL689438 | 0.65 | HPGD (0.35) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL91340 | 0.63 | ALDH1A1 (0.45) | PLA2G7MAPTHTTKDM4EALDH1A1 | |
| SCHEMBL9243614 | 0.62 | KDM4E (0.60) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9242590 | 0.62 | RXFP1 (0.52) | KMT2AMEN1 | |
| SCHEMBL3229953 | 0.62 | MAPT (0.40) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9819131 | 0.61 | GLA (0.31) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796251-B1 | URACIL DERIVATIVES | BYK GULDEN LOMBERG CHEM FAB (DE) | 2001-10-17 | — | — | EP | disclosed |
| EP-0796251-A1 | URACIL DERIVATIVES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1997-09-24 | — | — | EP | disclosed |
| WO-1996017831-A1 | URACIL DERIVATIVES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-06-13 | — | — | WO | disclosed |