Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.70 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803168 | 0.88 | TBXAS1 (0.54) | TBXAS1CYP11B2MAPTMAOAMAOB | |
| SCHEMBL7803145 | 0.88 | TBXAS1 (0.55) | TBXAS1CYP11B2MAPTMAOA | |
| SCHEMBL7811339 | 0.88 | TBXAS1 (0.55) | TBXAS1CYP11B2MAPT | |
| SCHEMBL7811601 | 0.88 | TBXAS1 (0.55) | TBXAS1CYP11B2MAPT | |
| SCHEMBL7803024 | 0.87 | TBXAS1 (0.53) | TBXAS1CYP11B2MAPTMAOAMAOB | |
| SCHEMBL11006075 | 0.83 | TBXAS1 (1.00) | TBXAS1CYP11B2MAPT | |
| SCHEMBL11009473 | 0.83 | TBXAS1 (1.00) | TBXAS1CYP11B2MAPT | |
| SCHEMBL3513494 | 0.83 | TBXAS1 (1.00) | TBXAS1CYP11B2MAPT | |
| SCHEMBL11009385 | 0.82 | TBXAS1 (0.85) | TBXAS1CYP11B2MAPTMAOAMAOB | |
| SCHEMBL11014108 | 0.82 | TBXAS1 (0.76) | TBXAS1CYP11B2MAPTMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |