Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809652 | 0.91 | TBXAS1 (0.48) | TBXAS1CYP11B2CYP11B1MAOAPTGES2 | |
| SCHEMBL7811339 | 0.89 | TBXAS1 (0.55) | TBXAS1CYP11B2CYP11B1PTGES2ESR1 | |
| SCHEMBL7811601 | 0.89 | TBXAS1 (0.55) | TBXAS1CYP11B2CYP11B1PTGES2ESR1 | |
| SCHEMBL11008497 | 0.88 | TBXAS1 (0.64) | TBXAS1CYP11B2CYP11B1MAOAPTGES2 | |
| SCHEMBL7803002 | 0.88 | TBXAS1 (0.70) | TBXAS1CYP11B2MAOAMAPT | |
| SCHEMBL10451457 | 0.84 | TBXAS1 (0.76) | TBXAS1CYP11B2CYP11B1MAOAPTGES2 | |
| SCHEMBL11015107 | 0.84 | TBXAS1 (0.64) | TBXAS1CYP11B2CYP11B1MAOAPTGES2 | |
| Hydrochloric Acid SCHEMBL11004741 | 0.83 | TBXAS1 (0.75) | TBXAS1CYP11B2CYP11B1MAOAPTGES2 | |
| Hydrochloric Acid SCHEMBL11007370 | 0.83 | TBXAS1 (0.57) | TBXAS1CYP11B2CYP11B1MAOAPTGES2 | |
| SCHEMBL7803168 | 0.82 | TBXAS1 (0.54) | TBXAS1CYP11B2MAOAMAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |