Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807925 | 0.87 | TBXAS1 (0.55) | TBXAS1MAPTESR1ESR2CYP11B2 | |
| Hydrochloric Acid SCHEMBL11007370 | 0.86 | TBXAS1 (0.57) | TBXAS1MAPTESR1ESR2CYP11B2 | |
| SCHEMBL11014108 | 0.85 | TBXAS1 (0.76) | TBXAS1MAPTESR1ESR2CYP11B2 | |
| SCHEMBL11009883 | 0.85 | TBXAS1 (0.76) | TBXAS1MAPTESR1ESR2CYP11B2 | |
| Hydrochloric Acid SCHEMBL11069109 | 0.85 | TBXAS1 (0.56) | TBXAS1MAPTESR1ESR2CYP11B2 | |
| Hydrochloric Acid SCHEMBL11069103 | 0.85 | TBXAS1 (0.56) | TBXAS1MAPTESR1ESR2CYP11B2 | |
| SCHEMBL7811601 | 0.84 | TBXAS1 (0.55) | TBXAS1MAPTESR1ESR2CYP11B2 | |
| SCHEMBL7811339 | 0.84 | TBXAS1 (0.55) | TBXAS1MAPTESR1ESR2CYP11B2 | |
| SCHEMBL1606827 | 0.83 | TBXAS1 (0.55) | TBXAS1MAPTESR1ESR2CYP11B2 | |
| SCHEMBL28107204 | 0.79 | CYP11B2 (0.59) | TBXAS1MAPTESR1CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |