SCHEMBL7803345

SCHEMBL7803345

N#Cc1cccc(-c2cc(C(=O)O)cc(C(=O)O)c2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.60
SLC22A12 Q96S37 1/20 0.60
DHODH Q02127 4/20 0.54
KAT6A Q92794 1/20 0.53
KMO O15229 1/20 0.50
CLK4 Q9HAZ1 1/20 0.50
IKBKB O14920 1/20 0.50
CHUK O15111 1/20 0.50
F11 P03951 1/20 0.49
PIN1 Q13526 1/20 0.49
RXRA P19793 1/20 0.49
RXRB P28702 1/20 0.49
IDO1 P14902 1/20 0.47
SYK P43405 1/20 0.47
PDE4A P27815 1/20 0.47
PDE4C Q08493 1/20 0.47
PDE4D Q08499 1/20 0.47
MMP12 P39900 1/20 0.47
MMP13 P45452 1/20 0.47
GSK3B P49841 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5529069 0.91 XDH (0.62) XDHSLC22A12KAT6AKMOCLK4
SCHEMBL4856931 0.87 TRIM24 (0.52) XDHSLC22A12DHODHKAT6AKMO
SCHEMBL6288226 0.87 XDH (0.51) XDHSLC22A12DHODHKAT6AKMO
SCHEMBL2034067 0.86 XDH (0.65) XDHSLC22A12KMOCLK4RXRA
SCHEMBL29788150 0.86 XDH (0.65) XDHSLC22A12KMOCLK4RXRA
SCHEMBL254013 0.84 XDH (0.54) XDHSLC22A12KAT6AKMOCLK4
SCHEMBL14784209 0.83 SYK (0.51) XDHSLC22A12DHODHKAT6AKMO
SCHEMBL5669424 0.83 DHODH (0.58) DHODHKMORXRARXRB
SCHEMBL5669446 0.83 DHODH (0.54) XDHSLC22A12DHODHKMORXRA
SCHEMBL16108317 0.81 KAT6A (0.59) XDHSLC22A12KAT6AKMOCLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2001335556-A METHOD FOR PRODUCING 5-(3-CYANOPHENYL)-3-FORMYLBENZOIC ACID DERIVATIVE TEIJIN LTD 2001-12-04 JP disclosed