SCHEMBL5669446

SCHEMBL5669446

C#Cc1cccc(-c2cc(C(=O)O)cc(C(=O)O)c2)c1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 6/20 0.54
KMO O15229 2/20 0.50
RXRA P19793 2/20 0.49
RXRB P28702 2/20 0.49
HAO1 Q9UJM8 1/20 0.45
XDH P47989 1/20 0.42
SLC22A12 Q96S37 1/20 0.42
FFAR1 O14842 1/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27716780 0.86 TRIM24 (0.54) KMORXRARXRBXDHSLC22A12
SCHEMBL5669424 0.83 DHODH (0.58) DHODHKMORXRARXRBHAO1
SCHEMBL7803345 0.83 XDH (0.60) DHODHKMORXRARXRBXDH
SCHEMBL5669171 0.81 GLRA3 (0.42) DHODHKMORXRARXRBHAO1
SCHEMBL30933040 0.81 DHODH (0.75) DHODHKMORXRARXRBLMNA
Hydrochloric Acid SCHEMBL6923143 0.80 GLRA3 (0.41) DHODHKMORXRARXRBHAO1
SCHEMBL256865 0.80 CA12 (0.52) KMOHAO1FFAR1
SCHEMBL29411053 0.80 CA12 (0.52) KMOHAO1FFAR1
SCHEMBL14538156 0.79 KMO (0.65) DHODHKMORXRARXRBLMNA
SCHEMBL28057748 0.79 ERN1 (0.49) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed