SCHEMBL7803372

SCHEMBL7803372

Fc1cccc(F)c1C1=NC(COc2ccc(Oc3ccccc3)cc2)CO1

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.43
TDP1 Q9NUW8 1/20 0.40
LTA4H P09960 3/20 0.38
FFAR4 Q5NUL3 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7812242 0.95 TAAR1 (0.46) TAAR1TDP1
SCHEMBL7812409 0.90 MEN1 (0.40) TAAR1
SCHEMBL7803617 0.90 TAAR1 (0.46) TAAR1LTA4HFFAR4
SCHEMBL7812313 0.90 TAAR1 (0.40) TAAR1FFAR4
SCHEMBL8308163 0.89 TAAR1 (0.56) TAAR1
SCHEMBL7812430 0.88 TAAR1 (0.37) TAAR1
SCHEMBL7803592 0.88 LTA4H (0.41) TAAR1LTA4H
SCHEMBL7808755 0.88 TAAR1 (0.47) TAAR1
SCHEMBL7812919 0.87 TAAR1 (0.37) TAAR1
SCHEMBL7803673 0.86 TAAR1 (0.41) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553623-B1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL CO (JP) 2001-04-04 EP disclosed
US-5556867-A INSECTICIDES AND MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-09-17 US disclosed
US-5411979-A Insecticides, miticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-05-02 US disclosed
EP-0553623-A1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-04 EP disclosed