SCHEMBL7803592

SCHEMBL7803592

Fc1cccc(F)c1C1=NC(COc2ccc(Cc3ccccc3)cc2)CO1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 0.41
TAAR1 Q96RJ0 3/20 0.39
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7808755 0.91 TAAR1 (0.47) TAAR1
SCHEMBL7812242 0.90 TAAR1 (0.46) TAAR1
SCHEMBL7803372 0.88 TAAR1 (0.43) LTA4HTAAR1
SCHEMBL7812313 0.88 TAAR1 (0.40) TAAR1NPC1POLBRAB9ASMN1; SMN2
SCHEMBL7803673 0.84 TAAR1 (0.41) TAAR1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL7803379 0.84 HRH3 (0.38) LTA4HTAAR1NPC1POLBRAB9A
SCHEMBL7812430 0.84 TAAR1 (0.37) TAAR1SMN1; SMN2
SCHEMBL7815858 0.84 TAAR1 (0.37) TAAR1NPC1POLBRAB9ASMN1; SMN2
SCHEMBL7809030 0.83 TAAR1 (0.46) TAAR1
SCHEMBL7809985 0.83 MAOB (0.42) TAAR1NPC1POLBRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553623-B1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL CO (JP) 2001-04-04 EP disclosed
US-5556867-A INSECTICIDES AND MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-09-17 US disclosed
US-5411979-A Insecticides, miticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-05-02 US disclosed
EP-0553623-A1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-04 EP disclosed