SCHEMBL7803435

SCHEMBL7803435

CCC(c1cc(OC)ccc1OC)C1CCCN(C(=O)C(=O)C(C)(C)CC)C1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 19/20 0.52
FKBP5 Q13451 4/20 0.43
FKBP4 Q02790 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7803438 0.78 FKBP1A (0.67) FKBP1AFKBP5FKBP4
SCHEMBL5700670 0.75 FKBP1A (0.44) FKBP1A
SCHEMBL5966055 0.74 FKBP1A (0.49) FKBP1AFKBP5FKBP4
SCHEMBL5965922 0.73 FKBP1A (0.53) FKBP1AFKBP5FKBP4
SCHEMBL5700683 0.73 FKBP1A (0.44) FKBP1A
SCHEMBL7424334 0.73 FKBP1A (0.64) FKBP1AFKBP5FKBP4
SCHEMBL5700583 0.72 FKBP1A (0.53) FKBP1A
SCHEMBL5965992 0.71 FKBP1A (0.57) FKBP1AFKBP5FKBP4
SCHEMBL5966154 0.71 FKBP1A (0.45) FKBP1A
SCHEMBL5966022 0.69 FKBP1A (0.52) FKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0777478-B1 INHIBITORS OF ROTAMASE ENZYME ACTIVITY GUILFORD PHARM INC (US) 2001-11-07 EP claimed
US-20010036947-A1 Pipecolic acid derivative hair growth compositions and uses GPI NIL HOLDINGS, INC. (US) 2001-11-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010036947-A1 Pipecolic acid derivative hair growth compositions and uses PIP5K1C, PIP4K2C, PIP5K1A FKBP1A 510/4885FKBP5 730/4885FKBP4 1140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.