Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 20/20 | 0.64 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.44 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6684784 | 0.78 | FKBP1A (1.00) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7422008 | 0.76 | FKBP1A (0.61) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7433188 | 0.76 | FKBP1A (0.59) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL5966173 | 0.76 | FKBP1A (1.00) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7803435 | 0.73 | FKBP1A (0.52) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL14920841 | 0.72 | FKBP1A (1.00) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL14920840 | 0.72 | FKBP1A (1.00) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL7803438 | 0.72 | FKBP1A (0.67) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL6604128 | 0.72 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL28331561 | 0.71 | FKBP1A (0.74) | FKBP1AMTORFKBP4FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002522485-A | — | — | 2002-07-23 | — | — | JP | claimed |
| EP-1109554-A2 | PIPECOLIC ACID DERIVATIVES FOR VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-27 | — | — | EP | claimed |
| EP-1083872-A1 | PIPECOLIC ACID DERIVATIVE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL Holdings, Inc. (US) | 2001-03-21 | — | — | EP | claimed |
| WO-2000009109-A2 | PIPECOLIC ACID DERIVATIVES FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | claimed |
| WO-1999062483-A1 | PIPECOLIC ACID DERIVATIVE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL HOLDINGS, INC. (US) | 1999-12-09 | — | — | WO | claimed |
| EP-1127049-A1 | BRIDGED HETEROCYCLIC DERIVATIVES | GPI NIL Holdings, Inc. (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-1011650-A1 | METHOD FOR PREVENTING AND TREATING HEARING LOSS USING SENSORINEUROTROPHIC COMPOUNDS | Amgen Inc., (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-2000016603-A2 | BRIDGED HETEROCYCLIC DERIVATIVES | GPI NIL HOLDINGS, INC. (US) | 2000-03-30 | — | — | WO | disclosed |
| WO-1999014998-A2 | METHOD FOR PREVENTING AND TREATING HEARING LOSS USING SENSORINEUROTROPHIC COMPOUNDS | AMGEN INC. (US) | 1999-04-01 | — | — | WO | disclosed |