Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804905 | 1.00 | HTR1D (0.65) | HTR1DHTR1B | |
| SCHEMBL7804051 | 0.90 | HTR1D (0.73) | HTR1DHTR1B | |
| SCHEMBL7804074 | 0.90 | HTR1D (0.62) | HTR1DHTR1B | |
| SCHEMBL7798117 | 0.84 | HTR1D (0.64) | HTR1DHTR1B | |
| SCHEMBL7808656 | 0.82 | GABRP (0.65) | HTR1DHTR1B | |
| SCHEMBL9021850 | 0.81 | HTR1B (0.68) | HTR1DHTR1B | |
| SCHEMBL9077698 | 0.81 | HTR1B (0.68) | HTR1DHTR1B | |
| SCHEMBL9117342 | 0.79 | HTR1D (0.53) | HTR1DHTR1B | |
| SCHEMBL8662143 | 0.78 | HTR1D (0.63) | HTR1DHTR1B | |
| SCHEMBL9117455 | 0.78 | HTR1D (0.54) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741722-B1 | TRIAZOLE DERIVATIVES | MERCK SHARP & DOHME (GB) | 2001-06-13 | — | — | EP | claimed |
| EP-0741722-A1 | TRIAZOLE DERIVATIVES | MERCK SHARP & DOHME LTD. (GB) | 1996-11-13 | — | — | EP | claimed |
| WO-1995021166-A1 | TRIAZOLE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1995-08-10 | — | — | WO | claimed |
| EP-0741722-B1 | TRIAZOLE DERIVATIVES | MERCK SHARP & DOHME (GB) | 2001-06-13 | — | — | EP | disclosed |
| EP-0741722-A1 | TRIAZOLE DERIVATIVES | MERCK SHARP & DOHME LTD. (GB) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995021166-A1 | TRIAZOLE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1995-08-10 | — | — | WO | disclosed |