Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.53 |
| ▸ | CTSB | P07858 | 15/20 | 0.53 |
| ▸ | CTSL | P07711 | 15/20 | 0.53 |
| ▸ | CTSK | P43235 | 12/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797635 | 0.88 | CTSS (0.71) | CTSSCTSBCTSLCTSK | |
| SCHEMBL3417585 | 0.88 | CTSS (0.59) | CTSSCTSBCTSLCTSK | |
| SCHEMBL7807933 | 0.79 | CTSS (0.74) | CTSSCTSBCTSLCTSK | |
| SCHEMBL8266815 | 0.74 | CTSL (0.57) | CTSSCTSBCTSLCTSK | |
| SCHEMBL8290553 | 0.73 | CTSS (0.56) | CTSSCTSBCTSLCTSK | |
| SCHEMBL8290818 | 0.72 | CTSS (0.55) | CTSSCTSBCTSLCTSK | |
| SCHEMBL8260389 | 0.71 | CTSS (0.47) | CTSSCTSBCTSLCTSK | |
| SCHEMBL3417962 | 0.69 | CTSS (0.82) | CTSSCTSBCTSLCTSK | |
| SCHEMBL7807773 | 0.69 | CTSS (1.00) | CTSSCTSBCTSLCTSK | |
| SCHEMBL7811944 | 0.69 | CTSL (0.76) | CTSSCTSBCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010148488-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS FOR THE TREATMENT OF VARIOUS DISEASES | MERCK FROSST CANADA LTD. (CA) | 2010-12-29 | — | — | WO | disclosed |