Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 13/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805351 | 1.00 | CXCR2 (0.37) | CXCR2TEAD4PGRARTP53 | |
| Hydrochloric Acid SCHEMBL7795371 | 0.86 | CXCR2 (0.39) | CXCR2TEAD4LMNAMAPTHTT | |
| SCHEMBL7787857 | 0.84 | S1PR3 (0.40) | CXCR2TEAD4PGRARTP53 | |
| SCHEMBL7780328 | 0.84 | S1PR3 (0.40) | CXCR2TEAD4PGRARTP53 | |
| SCHEMBL7805393 | 0.80 | CXCR2 (0.40) | CXCR2TEAD4MAPKAPK2CCR6 | |
| SCHEMBL7795412 | 0.80 | CXCR2 (0.40) | CXCR2TEAD4MAPKAPK2CCR6 | |
| Hydrochloric Acid SCHEMBL7803652 | 0.79 | CXCR2 (0.39) | CXCR2TEAD4MAPKAPK2CCR6 | |
| SCHEMBL7802233 | 0.78 | CXCR2 (0.39) | CXCR2TEAD4LMNAMAPKAPK2CCR6 | |
| Hydrochloric Acid SCHEMBL7801936 | 0.77 | MAPKAPK2 (0.41) | CXCR2MAPKAPK2CCR6 | |
| SCHEMBL7801221 | 0.73 | CXCR2 (0.41) | CXCR2TEAD4MAPKAPK2CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |