Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813594 | 0.82 | KDM4E (0.52) | KDM4EKMT2AMEN1SMN1; SMN2NLRP3 | |
| SCHEMBL7816985 | 0.81 | ALDH1A1 (0.53) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29859446 | 0.80 | KDM4E (0.66) | KDM4EKMT2AMEN1SMN1; SMN2NLRP3 | |
| SCHEMBL9730724 | 0.80 | KDM4E (0.66) | KDM4EKMT2AMEN1SMN1; SMN2NLRP3 | |
| SCHEMBL11389359 | 0.77 | ALDH1A1 (0.63) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9147032 | 0.76 | KDM4E (0.51) | KDM4EKMT2AMEN1SMN1; SMN2NLRP3 | |
| SCHEMBL2384520 | 0.74 | KDM4E (0.53) | KDM4EKMT2AMEN1SMN1; SMN2NLRP3 | |
| SCHEMBL9531872 | 0.73 | KDM4E (0.49) | KDM4EKMT2AMEN1SMN1; SMN2NLRP3 | |
| SCHEMBL4065612 | 0.73 | KDM4E (0.72) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11291425 | 0.73 | KDM4E (0.48) | KDM4EKMT2AMEN1SMN1; SMN2NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533882-B1 | 2-QUINOLINONE DERIVATIVES, METHODS FOR PREPARING THE SAME AND FUNGICIDES AND INSECTICIDES INCLUDING THEM | KOREA RES INST CHEM TECH (KR) | 2001-02-07 | — | — | EP | disclosed |
| US-5430153-A | Insecticides, fungicides | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-07-04 | — | — | US | disclosed |
| WO-1992017452-A1 | 2-QUINOLINONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-10-15 | — | — | WO | disclosed |